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  • 产品名称：C17orf67抗原（重组蛋白）

  • 产品型号：1mg
  • 产品厂商：通蔚生物
  • 产品价格：3580
  • 产品库存：35
  • 产品文档：
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简单介绍：
C17orf67抗原（重组蛋白）公司的服务和业务网络遍及国内，在同行获得一致好评，将一直伴随着顾客的信赖成长，规模和抗体种类日益扩大和更新，一直秉承着代理上等品牌的产品，服务好每一位顾客，将好的科学技术和方法推荐给顾客的服务宗旨。
详情介绍：

中文名称： C17orf67抗原（重组蛋白）

英文名称： C17orf67 Antigen (Recombinant Protein)

相关类别： 抗原

储     存： 冷冻（-20℃）

概     述

Fusion protein corresponding to a region derived from 43-114 amino acids of human C17orf67

技术规格

Full name:

chromosome 17 open reading frame 67

Swissprot:

Q0P5P2

Gene Accession:

BC093905

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

C17orf67 (chromosome 17 open reading frame 67) is a 114 amino acid protein that is encoded by a gene mapping to human chromosome 17. Chromosome 17 makes up over 2.5% of the human genome with about 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17.




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