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  • 产品名称：C9orf116 抗原（重组蛋白）

  • 产品型号：100ug
  • 产品厂商：通蔚生物
  • 产品价格：800
  • 产品库存：35
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C9orf116 抗原（重组蛋白）公司的服务和业务网络遍及国内，在同行获得一致好评，将一直伴随着顾客的信赖成长，规模和抗体种类日益扩大和更新，一直秉承着代理上等品牌的产品，服务好每一位顾客，将好的科学技术和方法推荐给顾客的服务宗旨。
详情介绍：

中文名称： C9orf116 抗原（重组蛋白）

英文名称： C9orf116 Antigen (Recombinant Protein)

别     名： chromosome 9 open reading frame 116; PIERCE1; RbEST47

储     存： 冷冻（-20℃）

相关类别：抗原

概     述

Fusion protein corresponding to a region derived from 1-92 amino acids of human C9orf116


技术规格

Full name:

chromosome 9 open reading frame 116

Synonyms:

PIERCE1; RbEST47

Swissprot:

Q5BN46

Gene Accession:

BC021261

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

C9orf116, also known as PIERCE1. PIERCE1 is an important p53 target gene contributing to normal DNA damage response and may play crucial roles in maintaining genomic integrity against genotoxic stresses, including UVC irradiation. PIERCE1 exists as two alternatively spliced isoforms and is predominantly expressed in human small cell lung cancer. PIERCE1 knockdown induces down-regulation of proapoptotic genes including Ei24, Apaf1 and PTEN, suggesting that PIERCE1 is a proapoptotic gene. It is helpful for in-depth understanding of p53 pathways and the design of new cancer therapies.





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