|
Full name: |
PDZ and LIM domain 2 (mystique) |
|
Synonyms: |
SLIM; MYSTIQUE |
|
Swissprot: |
Q96JY6 |
|
Gene Accession: |
BC021556 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
This gene encodes a member of the ALP subfamily of PDZ-LIM domain proteins. The encoded protein suppresses anchorage-dependent growth and promotes cell migration and adhesion through interactions with the actin cytoskeleton via the PDZ domain. The encoded protein is also a putative tumor suppressor protein, and decreased expression of this gene is associated with several malignancies including breast cancer and ***** T-cell leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
