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  • 产品名称:NFKBIA抗原(重组蛋白)

  • 产品型号:1mg
  • 产品厂商:通蔚生物
  • 产品价格:3580
  • 产品库存:35
  • 产品文档:
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详情介绍:


中文名称: NFKBIA抗原(重组蛋白)

英文名称: NFKBIA Antigen (Recombinant Protein)
 
储     存:  冷冻(-20℃)

相关类别: 抗原

概     述

Fusion protein corresponding to a region derived from 1-317 amino acids of human NFKBIA

技术规格

Full name:

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha

Synonyms:

IKBA; MAD-3; NFKBI

Swissprot:

P25963

Gene Accession:

BC004983

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.





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