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  • 产品名称:NFKBID抗原(重组蛋白)

  • 产品型号:1mg
  • 产品厂商:通蔚生物
  • 产品价格:3580
  • 产品库存:35
  • 产品文档:
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详情介绍:


中文名称: NFKBID抗原(重组蛋白)

英文名称: NFKBID Antigen (Recombinant Protein)

储      存: 冷冻(-20℃)

相关类别: 抗原

概      述

Fusion protein corresponding to a region derived from 1-221 amino acids of human NFKBID

技术规格

Full name:

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta

Synonyms:

TA-NFKBH, IkappaBNS

Swissprot:

Q8NI38

Gene Accession:

BC006273

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

May regulate the expression of IL-2, IL-6, and other cytokines through regulation on NF-kappa-B activity. Functions in the regulation of inflammatory responses. May also regulate TCR-induced negative selection of thymocytes.IκBNS, the nuclear IκB-like protein encoded by Nfkbid, is required for the development of marginal zone and peritoneal B-1 B cells and additionally required for extrafollicular antibody responses to T-independent and -dependent immunogens.IκBNS has been identified as a member of the IκB family of NF-κB inhibitors, which undergoes induction upon TCR signaling. IκBNS mediates both positive and negative gene regulation, depending on individual cell type and/or cytokine.





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