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  • 产品名称:MRE11 抗原(重组蛋白)

  • 产品型号:100ug
  • 产品厂商:通蔚生物
  • 产品价格:800
  • 产品库存:35
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中文名称: MRE11 抗原(重组蛋白)

英文名称: MRE11 Antigen (Recombinant Protein)

别     名:  MRE11 homolog, double strand break repair nuclease; ATLD; HNGS1; MRE11A; MRE11B

储     存:  冷冻(-20℃)

相关类别: 抗原

概    述

Fusion protein corresponding to N terminal 180 amino acids of human MRE11

技术规格

Full name:

MRE11 homolog, double strand break repair nuclease

Synonyms:

ATLD; HNGS1; MRE11A; MRE11B

Swissprot:

P49959

Gene Accession:

NP_005582

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.





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