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  • 产品名称:ITGB5抗原(重组蛋白)

  • 产品型号:1mg
  • 产品厂商:通蔚生物
  • 产品价格:3580
  • 产品库存:35
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详情介绍:


中文名称: ITGB5抗原(重组蛋白)

英文名称: ITGB5 Antigen (Recombinant Protein)

储     存:  冷冻(-20℃)

相关类别: 抗原

概     述

Fusion protein corresponding to a region derived from 136-378 amino acids of human ITGB5

技术规格

Full name:

integrin, beta 5

Swissprot:

P18084

Gene Accession:

BC006541

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Integrins are heterodimers composed of noncovalently associated transmembrane a and b subunits. The 16 a and 8 b subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, Collagen and Vitronectin. Certain integrins can also bind to soluble ligands such as Fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors.







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