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  • 产品名称:IRAK4抗原(重组蛋白)

  • 产品型号:1mg
  • 产品厂商:通蔚生物
  • 产品价格:3580
  • 产品库存:35
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详情介绍:


中文名称: IRAK4抗原(重组蛋白)

英文名称: IRAK4 Antigen (Recombinant Protein)

别     名:  IPD1; REN64; IRAK-4; NY-REN-64

储     存:  冷冻(-20℃)

相关类别: 抗原

概     述 

usion protein corresponding to a region derived from 186-454 amino acids of human IRAK4

技术规格

Full name:

interleukin-1 receptor-associated kinase 4

Synonyms:

IPD1; REN64; IRAK-4; NY-REN-64

Swissprot:

Q9NWZ3

Gene Accession:

BC013316

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.





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