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  • 产品名称：IRF9抗原（重组蛋白）

  • 产品型号：1mg
  • 产品厂商：通蔚生物
  • 产品价格：3580
  • 产品库存：35
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IRF9抗原（重组蛋白）有一支专业化的销售和技术服务团队，成熟化的专业性配备实验室，力求售前、售中、售后专业、快捷、方便、及时，经营原则是质量**，诚信为本，以质量是企业的生命，诚信是经营的资本为警醒，严把所售出商品的质量关。欢迎来电咨询订购！
详情介绍：



中文名称： IRF9抗原（重组蛋白）

英文名称：  IRF9 Antigen (Recombinant Protein)

别     名：   p48; IRF-9; ISGF3; ISGF3G

储     存：  冷冻（-20℃）

相关类别： 抗原

概      述

Fusion protein corresponding to a region derived from 188-393 amino acids of human IRF9

技术规格

Full name:

interferon regulatory factor 9

Synonyms:

p48; IRF-9; ISGF3; ISGF3G

Swissprot:

Q00978

Gene Accession:

BC035716

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Interferon regulatory factor 9 is a protein that in humans is encoded by the IRF9 gene, previously known as ISGF3G. Transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.







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