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  • 产品名称:INHBA抗原(重组蛋白)

  • 产品型号:1mg
  • 产品厂商:通蔚生物
  • 产品价格:3580
  • 产品库存:35
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详情介绍:



中文名称: INHBA抗原(重组蛋白)

英文名称: INHBA Antigen (Recombinant Protein)

别     名:  EDF; FRP

储     存:  冷冻(-20℃)

相关类别: 抗原

概     述
  
Fusion protein corresponding to a region derived from 311-426 amino acids of human INHBA

技术规格

Full name:

inhibin, beta A

Synonyms:

EDF; FRP

Swissprot:

P08476

Gene Accession:

BC007858

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion.






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