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  • 产品名称：IPO4 抗原（重组蛋白）

  • 产品型号：100ug
  • 产品厂商：通蔚生物
  • 产品价格：800
  • 产品库存：35
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IPO4 抗原（重组蛋白）有一支专业化的销售和技术服务团队，成熟化的专业性配备实验室，力求售前、售中、售后专业、快捷、方便、及时，经营原则是质量**，诚信为本，以质量是企业的生命，诚信是经营的资本为警醒，严把所售出商品的质量关。欢迎来电咨询订购！
详情介绍：


中文名称： IPO4 抗原（重组蛋白）

英文名称： IPO4 Antigen (Recombinant Protein)

别     名：  importin 4; Imp4

储     存：  冷冻（-20℃）

相关类别： 抗原

概     述

Fusion protein corresponding to C terminal 250amino acids of human IPO4

技术规格

Full name:

importin 4

Synonyms:

Imp4

Swissprot:

Q8TEX9

Gene Accession:

BC003690

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Importin-4 is a protein that in humans is encoded by the IPO4 gene. Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran.





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