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  • 产品名称：IKBIP 抗原（重组蛋白）

  • 产品型号：100ug
  • 产品厂商：通蔚生物
  • 产品价格：800
  • 产品库存：35
  • 产品文档：
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简单介绍：
IKBIP 抗原（重组蛋白）一直视质量控制为企业的生命，追求企业竞争力的不断提升，始终秉承信誉为生存之本的宗旨，以过硬的质量和优良的服务来维护和拓展市场，*大限度的满足客户的需求，与客户共赢，是我们的发展目标，愿与您精诚合作，共创美好的未来。
详情介绍：


中文名称： IKBIP 抗原（重组蛋白）

英文名称： IKBIP Antigen (Recombinant Protein)

别     名：  IKBKB interacting protein; IKIP

储     存：  冷冻（-20℃）

相关类别： 抗原

概     述

Fusion protein corresponding to a region derived from 71-350 amino acids of human IKBIP

技术规格

Full name:

IKBKB interacting protein

Synonyms:

IKIP

Swissprot:

Q70UQ0

Gene Accession:

BC058933

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

IKIP (Inhibitor of nuclear factor kappa-B kinase-interacting protein, IKK-interacting protein) is a single-pass membrane protein that shares a common promoter with APAF1. APAF1 and IKIP are both induced by X irradiation, however, the two gene products are transcribed in different directions. The IKIP gene is believed to be a target for p53 as expression of IKIP has been shown to promote apoptosis. IKIP has four known isoforms, three of which are found traversing the endoplasmic reticulum membrane. IKIP isoform 4 has a deletion of the transmembrane region which leads to a homogenous distribution of the protein within the cell. The IKIP gene products are expressed in vascular endothelial cells, while the isoform 4 has also been detected in lung, kidney, spleen, thymus and skeletal muscle.





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