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  • 产品名称：GDNF抗原（重组蛋白）

  • 产品型号：1mg
  • 产品厂商：通蔚生物
  • 产品价格：3580
  • 产品库存：35
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详情介绍：


中文名称： GDNF抗原（重组蛋白）

英文名称： GDNF Antigen (Recombinant Protein)

储     存：  冷冻（-20℃）

相关类别： 抗原

概     述

Fusion protein corresponding to a region derived from 20-211 amino acids of human GDNF

技术规格

Full name:

glial cell derived neurotrophic factor

Synonyms:

ATF1; ATF2; HSCR3; HFB1-GDNF

Swissprot:

P39905

Gene Accession:

BC069369

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. The encoded protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. Multiple transcript variants encoding different isoforms have been found for this gene. Mutations in this gene may be associated with Hirschsprung disease.





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