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  • 产品名称：GCDH 抗原（重组蛋白）

  • 产品型号：100ug
  • 产品厂商：通蔚生物
  • 产品价格：800
  • 产品库存：35
  • 产品文档：
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详情介绍：


中文名称： GCDH 抗原（重组蛋白）

英文名称： GCDH Antigen (Recombinant Protein)

别     名：  glutaryl-CoA dehydrogenase; GCD; ACAD5
  
储     存：  冷冻（-20℃）

相关类别： 抗原

概     述

Fusion protein corresponding to a region derived from 239-438 amino acids of human GCDH

技术规格

Full name:

glutaryl-CoA dehydrogenase

Synonyms:

GCD; ACAD5

Swissprot:

Q92947

Gene Accession:

BC002579

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits. Mutations in this gene result in the metabolic disorder glutaric aciduria type 1, which is also known as glutaric acidemia type I. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 12.





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