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  • 产品名称:DUSP10抗原(重组蛋白)

  • 产品型号:1mg
  • 产品厂商:通蔚生物
  • 产品价格:3580
  • 产品库存:35
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我司DUSP10抗原(重组蛋白)是一家集研发、生产、销售、服务于一体的国际**生物******,专业提供抗体、蛋白、Elisa试剂盒、细胞等生物产品,产品种类齐全、质量可靠、价格优惠,我司致力于向国内生命科学研究人员提供**的产品和服务。
详情介绍:


中文名称: DUSP10抗原(重组蛋白)

英文名称: DUSP10 Antigen (Recombinant Protein)

储     存:  冷冻(-20℃)

相关类别: 抗原

概     述

Fusion protein corresponding to C terminal 200 amino acids of human DUSP10

技术规格

Full name:

dual specificity phosphatase 10

Synonyms:

MKP5; MKP-5

Swissprot:

Q9Y6W6

Gene Accession:

BC031405

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAPK superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAPKs, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product binds to and inactivates p38 and SAPK/JNK, but not MAPK/ERK. Its subcellular localization is unique; it is evenly distributed in both the cytoplasm and the nucleus.





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