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  • 产品名称：DTX3L抗原（重组蛋白）

  • 产品型号：1mg
  • 产品厂商：通蔚生物
  • 产品价格：3580
  • 产品库存：35
  • 产品文档：
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简单介绍：
我司DTX3L抗原（重组蛋白）是一家集研发、生产、销售、服务于一体的国际**生物******，专业提供抗体、蛋白、Elisa试剂盒、细胞等生物产品，产品种类齐全、质量可靠、价格优惠，我司致力于向国内生命科学研究人员提供**的产品和服务。
详情介绍：


中文名称： DTX3L抗原（重组蛋白）

英文名称： DTX3L Antigen (Recombinant Protein)
 
储     存：  冷冻（-20℃）

相关类别： 抗原

概     述

Fusion protein corresponding to a region derived from 441-740 amino acids of human DTX3L

技术规格

Full name:

deltex E3 ubiquitin ligase 3L

Synonyms:

BBAP

Swissprot:

Q8TDB6

Gene Accession:

BC042191

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The Deltex family is responsible for influencing Notch signaling and may regulate transcription through interactions with specific transcription factors. Deltex proteins have a basic N-terminus, a central proline-rich region and a C-terminal RING-type zinc finger domain, a motif often found in ubiquitin-protein isopeptide ligases (E3). The RING-type zinc finger domain binds two Zn2+ atoms and forms a cross-brace motif that is essential for many proteins involved the ubiquitination pathway. DTX3L (Deltex-3-like), also known as BBAP, is a 740 amino acid protein that is similar to Deltex-3 and acts as a ubiquitin ligase in vitro. DTX3L can heterodimerize with Deltex-1, a transcriptional regulator, thereby enhancing the activity of the E3 ubiquitin ligase complex and increasing the influence of E3 on the Notch signaling pathway.





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