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  • 产品名称：DOK3抗原（重组蛋白）

  • 产品型号：1mg
  • 产品厂商：通蔚生物
  • 产品价格：3580
  • 产品库存：35
  • 产品文档：
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简单介绍：
我司的DOK3抗原（重组蛋白）受到了广大科研单位的一致肯定和认同，产品有保证，价格公道，倾力为国内外科研院校实验室提供*上等的产品。若有需要，我司将竭诚为您服务，欢迎广大用户来电来涵购买！当天生产，发货及时，国内包邮。
详情介绍：


中文名称： DOK3抗原（重组蛋白）

英文名称： DOK3 Antigen (Recombinant Protein)

储     存：  冷冻（-20℃）

相关类别： 抗原

概     述

Fusion protein corresponding to C terminal 300 amino acids of human DOK3

技术规格

Full name:

docking protein 3

Synonyms:

DOKL

Swissprot:

Q7L591

Gene Accession:

BC004564

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

DOK3 gene maps to chromosome 5q35.3. Dok3 was tyrosine phosphorylated by Src family members Lck, Fyn, and Lyn. Immunoprecipitation studies showed that Dok3 bound inhibitors SHIP and Csk but did not bind RasGAP. Dok3 binding to SHIP occurred via the SH2 domain. Dok3 also bound Csk via the Csk SH2 domain with possible involvement of the Csk SH3 domain as well.DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate ABL1 function





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