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  • 产品名称:CYP1A1抗原(重组蛋白)

  • 产品型号:1mg
  • 产品厂商:通蔚生物
  • 产品价格:3580
  • 产品库存:35
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详情介绍:


中文名称: CYP1A1抗原(重组蛋白)

英文名称: CYP1A1 Antigen (Recombinant Protein)

储     存:  冷冻(-20℃)

相关类别: 抗原

概     述

Fusion protein corresponding to a region derived from 213-512 amino acids of human CYP1A1

技术规格

Full name:

cytochrome P450 family 1 subfamily A member 1

Synonyms:

AHH; AHRR; CP11; CYP1; CYPIA1; P1-450; P450-C; P450DX

Swissprot:

P04798

Gene Accession:

BC023019

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. Alternative splicing results in multiple transcript variants encoding distinct isoforms.





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