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Full name: |
cyclin and CBS domain divalent metal cation transport mediator 3 |
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Synonyms: |
ACDP3 |
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Swissprot: |
Q8NE01 |
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Gene Accession: |
BC007199 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The ACDP3 gene, designated CNNM3 by the HUGO Nomenclature Committee, encodes a deduced 707-amino acid protein. Northern blot analysis revealed ubiquitous expression of CNNM3. Immunofluorescence studies showed that all 4 CNMM proteins are predominantly localized in the nucleus. Acdp3 contains 4 transmembrane domains, 2 CBS domains, a DUF21 domain, and a cNMP-binding domain. It also has large alanine- and leucine-rich regions. Northern blot analysis detected variable Acdp3 expression in all mouse tissues examined, with highest expression in brain, kidney, liver, and heart. |
