概 述
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Full name: |
cyclic nucleotide gated channel alpha 2 |
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Synonyms: |
CNCA, CNG2, CNCA1, OCNC1, OCNCa, OCNCALPHA |
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Swissprot: |
Q16280 |
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Gene Accession: |
BC126302 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The protein encoded by this gene represents the alpha subunit of a cyclic nucleotide-gated olfactory channel. The encoded protein contains a carboxy-terminal leucine zipper that mediates channel formation. Odorant signal transduction is probably mediated by a G-protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons. |
