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  • 产品名称：CDK4抗原（重组蛋白）

  • 产品型号：1mg
  • 产品厂商：通蔚生物
  • 产品价格：3580
  • 产品库存：35
  • 产品文档：
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简单介绍：
针对不同行业的需求，我司不断完善、更新技术和方法。CDK4抗原（重组蛋白）在实验室应用的比较广泛，被业内众多的科研人士认可和推广。公司以上等，齐全的抗体产品和上等的技术团队得到了国家各大实验高校及科研单位的认可和赞誉，拥有和好的知名度和口碑。
详情介绍：


中文名称： CDK4抗原（重组蛋白）

英文名称： CDK4 Antigen (Recombinant Protein)

储     存：  冷冻（-20℃）

相关类别： 抗原

概     述

Fusion protein corresponding to a region derived from 1-303 amino acids of human CDK4

技术规格

Full name:

cyclin dependent kinase 4

Synonyms:

CMM3; PSK-J3

Swissprot:

P11802

Gene Accession:

BC003644

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported.





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