产品中心
产品详情
查看大图

  • 产品名称：CALR抗原（重组蛋白）

  • 产品型号：1mg
  • 产品厂商：通蔚生物
  • 产品价格：3580
  • 产品库存：35
  • 产品文档：
你添加了1件商品 查看购物车
简单介绍：
CALR抗原（重组蛋白）打造了一支训练有素的技术团队，为抗体产品质量提供了强有力的保障，一直致力于研发生产高质量的科研试剂，为生命科学提供**的蛋白检测相关产品，先进的实验设备，强大的技术力量，诚信的服务态度是您实验成果的保障！
详情介绍：


中文名称： CALR抗原（重组蛋白）

英文名称： CALR Antigen (Recombinant Protein)

储     存：  冷冻（-20℃）

相关类别： 抗原

概     述

Fusion protein corresponding to a region derived from 20-218 amino acids of human CALR

技术规格

Full name:

Calreticulin

Synonyms:

RO; CRT; SSA; cC1qR

Swissprot:

P27797

Gene Accession:

BC002500

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Calreticulin is a multifunctional protein that acts as a major Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. It is also found in the nucleus, suggesting that it may have a role in transcription regulation. Calreticulin binds to the synthetic peptide KLGFFKR, which is almost identical to an amino acid sequence in the DNA-binding domain of the superfamily of nuclear receptors. Calreticulin binds to antibodies in certain sera of systemic lupus and Sjogren patients which contain anti-Ro/SSA antibodies, it is highly conserved among species, and it is located in the endoplasmic and sarcoplasmic reticulum where it may bind calcium. The amino terminus of calreticulin interacts with the DNA-binding domain of the glucocorticoid receptor and prevents the receptor from binding to its specific glucocorticoid response element.





姓名：
电话：
您的需求：