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  • 产品名称：BIN1抗原（重组蛋白）

  • 产品型号：1mg
  • 产品厂商：通蔚生物
  • 产品价格：3580
  • 产品库存：35
  • 产品文档：
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简单介绍：
BIN1抗原（重组蛋白）打造了一支训练有素的技术团队，为抗体产品质量提供了强有力的保障，一直致力于研发生产高质量的科研试剂，为生命科学提供**的蛋白检测相关产品，先进的实验设备，强大的技术力量，诚信的服务态度是您实验成果的保障！
详情介绍：


中文名称： BIN1抗原（重组蛋白）

英文名称： BIN1 Antigen (Recombinant Protein)

储     存： 冷冻（-20℃）

相关类别： 抗原

概     述

Fusion protein corresponding to C terminal 250 amino acids of human BIN1

技术规格

Full name:

bridging integrator 1

Synonyms:

AMPH2; AMPHL; SH3P9

Swissprot:

O00499

Gene Accession:

BC004101

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in ten transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described.





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