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  • 产品名称：BCL2A1抗原（重组蛋白）

  • 产品型号：1mg
  • 产品厂商：通蔚生物
  • 产品价格：3580
  • 产品库存：35
  • 产品文档：
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简单介绍：
BCL2A1抗原（重组蛋白）打造了一支训练有素的技术团队，为抗体产品质量提供了强有力的保障，一直致力于研发生产高质量的科研试剂，为生命科学提供**的蛋白检测相关产品，先进的实验设备，强大的技术力量，诚信的服务态度是您实验成果的保障！
详情介绍：


中文名称： BCL2A1抗原（重组蛋白）

英文名称： BCL2A1 Antigen (Recombinant Protein)

储     存：  冷冻（-20℃）

相关类别： 抗原

概     述

Fusion protein corresponding to a region derived from 1-175 amino acids of human BCL2A1

技术规格

Full name:

BCL2-related protein A1

Synonyms:

GRS; BFL1; ACC-1; ACC-2; HBPA1; BCL2L5

Swissprot:

Q16548

Gene Accession:

BC016281

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.





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