相关类别： 抗原
概 述
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Full name: |
tribbles pseudokinase 3 |
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Synonyms: |
NIPK; SINK; TRB3; SKIP3; C20orf97 |
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Swissprot: |
Q96RU7 |
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Gene Accession: |
BC019363 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1. Differential promoter usage and alternate splicing result in multiple transcript variants. |
