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  • 产品名称：SLFN5 抗原（重组蛋白）

  • 产品型号：1mg
  • 产品厂商：通蔚生物
  • 产品价格：3580
  • 产品库存：35
  • 产品文档：
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简单介绍：
根据数据统计 SLFN5 抗原（重组蛋白）在同类产品中销量很好，实验效果显著。我司具有明显的价格优势，在保障产品质量条件下不断提升技术降低成本，使各项指标越开越**。可以满足生物化学、分子生物学、细胞生物学、免疫学等生物实验需求。
详情介绍：


中文名称： SLFN5 抗原（重组蛋白）

英文名称： SLFN5 Antigen (Recombinant Protein)

别     名：  schlafen family member 5

储     存：  冷冻（-20℃）

相关类别： 抗原

概     述

Fusion protein corresponding to a region derived from 139-338 amino acids of human SLFN5

技术规格

Full name:

schlafen family member 5

Swissprot:

Q08AF3

Gene Accession:

BC021238

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Slfn5 (schlafen family member 5) is an 891 amino acid protein that exists as multiple alternatively spliced isoforms and is thought to play a role in hematopoeitic cell differentiation. The gene encoding Slfn5 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.






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