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  • 产品名称：PCP4抗原（重组蛋白）

  • 产品型号：1mg
  • 产品厂商：通蔚生物
  • 产品价格：3580
  • 产品库存：35
  • 产品文档：
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简单介绍：
根据数据统计 PCP4抗原（重组蛋白）在同类产品中销量很好，实验效果显著。我司具有明显的价格优势，在保障产品质量条件下不断提升技术降低成本，使各项指标越开越**。可以满足生物化学、分子生物学、细胞生物学、免疫学等生物实验需求。
详情介绍：


中文名称： PCP4抗原（重组蛋白）

英文名称： PCP4 Antigen (Recombinant Protein)

储     存：  冷冻（-20℃）

相关类别： 抗原

概     述

Fusion protein corresponding to a region derived from N terminal 61 amino acids of human PCP4

技术规格

Full name:

purkinje cell protein 4

Synonyms:

PEP-19

Swissprot:

P48539

Gene Accession:

BC013791

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

PCP-4 (Purkinje cell protein 4), also known as PEP-19, is a calmodulin (CaM) regulatory protein that is highly expressed in neuronal cells. Through its IQ motif, PCP-4 mediates both the calcium-dependent binding properties of CaM and the rates of association and dissociation of calcium from the C-terminal domain of CaM. The IQ motif contains a serine residue which can be phosphorylated by all isoforms of protein kinase C (PKC). PCP-4 is implicated in uterine leiomyomas, as well as in neurodegenerative disorders such as Alzheimer’s disease and Huntington's disease. Additionally, overexpression of PCP-4 is thought to play a role in cerebellar hypoplasia, a key feature of Down syndrome.






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