储 存： 冷冻（-20℃）
相关类别： 抗原
概 述
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Full name: |
KH domain containing, RNA binding, signal transduction associated 3 |
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Synonyms: |
Etle; SALP; SLM2; SLM-2; TSTAR; T-STAR; etoile |
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Swissprot: |
O75525 |
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Gene Accession: |
BC032606 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. May play a role as a negative regulator of cell growth. Inhibits cell proliferation. Involved in splice site selection of vascular endothelial growth factor. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. RNA-binding abilities are down-regulated by tyrosine kinase PTK6. Involved in post-transcriptional regulation of HIV-1 gene expression. Binds preferentially to the 5'-[AU]UAAA-3' motif in vitro. |
