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  • 产品名称:IDO2抗原(重组蛋白)

  • 产品型号:1mg
  • 产品厂商:通蔚生物
  • 产品价格:3580
  • 产品库存:35
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详情介绍:

中文名称: IDO2抗原(重组蛋白)

英文名称: IDO2 Antigen (Recombinant Protein)

别     名:  INDOL1

储     存:  冷冻(-20℃)

相关类别: 抗原

概     述

Full length fusion protein

技术规格

Full name:

indoleamine 2,3-dioxygenase 2

Synonyms:

INDOL1

Swissprot:

Q6ZQW0

Gene Accession:

BC113496

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

INDOL1 is also known as IDO2 (indoleamine 2,3-dioxygenase 2) and is a 407 amino acid protein that is expressed in various tissues, including liver, small intestine, spleen, placenta, thymus, lung, brain, kidney, colon and dendritic cells. INDOL1 is selectively inhibited by D-1MT (1-methyl-d-tryptophan), which also inhibits IDO (indoleamine 2,3-dioxygenase) and is significant because IDO expression causes suppression of T cell responses to tumors in dendritic cells. The inhibition of INDOL1 by D-1MT suggests a common function in immunomodulation. In the human INDOL1 gene, two single nucleotide polymorphisms have been detected which abolish the enzymatic function of INDOL1.





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