概 述
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Full name: |
hydroxyprostaglandin dehydrogenase 15-(NAD) |
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Synonyms: |
PGDH; PGDH1; PHOAR1; 15-PGDH; SDR36C1 |
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Swissprot: |
P15428 |
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Gene Accession: |
BC018986 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a member of the short-chain nonmetalloenzyme alcohol dehydrogenase protein family. The encoded enzyme is responsible for the metabolism of prostaglandins, which function in a variety of physiologic and cellular processes such as inflammation. Mutations in this gene result in primary autosomal recessive hypertrophic osteoarthropathy and cranioosteoarthropathy. Multiple transcript variants encoding different isoforms have been found for this gene. |
