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  • 产品名称: 兔抗MAPK8多克隆抗体

  • 产品型号:100ul
  • 产品厂商:通蔚生物
  • 产品价格:1560
  • 产品库存:60
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详情介绍:


中文名称:  兔抗MAPK8多克隆抗体    

英文名称: Anti-MAPK8 rabbit polyclonal antibody

别      名: JNK, JNK1, PRKM8, SAPK1, JNK-46, JNK1A2, SAPK1c, JNK21B1/2

抗      原: MAPK8

储      存: 冷冻(-20℃)

宿      主: Rabbit

相关类别: 一抗

反应种属: Human, Mouse, Rat

标 记 物: Unconjugate

克隆类型: rabbit polyclonal

技术规格

Background:

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.

Applications:

ELISA, WB, IHC

Name of antibody:

MAPK8

Immunogen:

Fusion protein of human MAPK8

Full name:

mitogen-activated protein kinase 8

Synonyms:

JNK; JNK1; PRKM8; SAPK1; JNK-46; JNK1A2; SAPK1c; JNK21B1/2

SwissProt:

P45983

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human prostate cancer and Human liver cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

48 kDa

WB Positive control:

Jurkat, K562, Hela, A172 cell, Mouse brain tissue lysates

WB Recommended dilution:

500-2000




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