别 名： DRAL; AAG11; FHL-2; SLIM3; SLIM-3
概 述
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Full name: |
four and a half LIM domains 2 |
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Synonyms: |
DRAL; AAG11; FHL-2; SLIM3; SLIM-3 |
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Swissprot: |
Q14192 |
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Gene Accession: |
NP_963849 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. This protein is thought to have a role in the assembly of extracellular membranes. Also, this gene is down-regulated during transformation of normal myoblasts to rhabdomyosarcoma cells and the encoded protein may function as a link between presenilin-2 and an intracellular signaling pathway. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
