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  • 产品名称：FADD抗原（重组蛋白）

  • 产品型号：1mg
  • 产品厂商：通蔚生物
  • 产品价格：3580
  • 产品库存：35
  • 产品文档：
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简单介绍：
我司销售 FADD抗原（重组蛋白）款到发货，1天内发货，免费代测，七个工作日内出结果，保证结果质量。如遇到产品质量问题，免费退换货，如有销售人员不合作的情况，客户可打我司售后专线，我司对于问题员工会做相应的处理，优良保证客户的权利和利益。
详情介绍：

中文名称： FADD抗原（重组蛋白）

英文名称： FADD Antigen (Recombinant Protein)

储     存：  冷冻（-20℃）

相关类别： 抗原

概     述

Full length fusion protein

技术规格

Full name:

Fas (TNFRSF6)-associated via death domain

Synonyms:

GIG3, MORT1

Swissprot:

Q13158

Gene Accession:

BC000334

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development.





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