概 述
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Full name: |
echinoderm microtubule associated protein like 4 |
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Synonyms: |
C2orf2; ELP120; EMAP-4; EMAPL4; ROPP120 |
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Swissprot: |
Q9HC35 |
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Gene Accession: |
BC008685 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene is a member of the echinoderm microtubule associated protein-like family. The encoded WD-repeat protein may be involved in microtubule formation. Abnormal fusion of parts of this gene with portions of the anaplastic lymphoma receptor tyrosine kinase gene, which generates EML4-ALK fusion transcripts, is one of the primary mutations associated with non-small cell lung cancer. Alternative splicing of this gene results in two transcript variants. |
