别 名： P18; AIMP3
储 存： 冷冻（-20℃）
概 述
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Full name: |
eukaryotic translation elongation factor 1 epsilon 1 |
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Synonyms: |
P18; AIMP3 |
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Swissprot: |
O43324 |
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Gene Accession: |
BC005291 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, the encoded protein is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. However, its mouse homolog has been shown to translocate to the nucleus in response to DNA damage, and it plays a positive role in ATM/ATR-mediated p53 activation. Alternative splicing results in multiple transcript variants. |
