英文名称： CRADD Antigen (Recombinant Protein)
概 述
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Full name: |
CASP2 and RIPK1 domain containing adaptor with death domain |
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Synonyms: |
MRT34; RAIDD |
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Swissprot: |
P78560 |
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Gene Accession: |
BC037905 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The protein encoded by this gene is a death domain (CARD/DD)-containing protein and has been shown to induce cell apoptosis. Through its CARD domain, this protein interacts with, and thus recruits, caspase 2/ICH1 to the cell death signal transduction complex that includes tumor necrosis factor receptor 1 (TNFR1A), RIPK1/RIP kinase, and numbers of other CARD domain-containing proteins. |
