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  • 产品名称：TLR5抗原（重组蛋白）

  • 产品型号：100ug
  • 产品厂商：通蔚生物
  • 产品价格：800
  • 产品库存：35
  • 产品文档：
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详情介绍：

中文名称： TLR5抗原（重组蛋白）

英文名称： TLR5 Antigen (Recombinant Protein)

别     名：  TIL3; SLEB1

储     存：  冷冻（-20℃）

相关类别： 抗原

概     述：

Fusion protein corresponding to a region derived from 3-180 amino acids of human TLR5

技术规格

Full name:

toll-like receptor 5

Synonyms:

TIL3; SLEB1

Swissprot:

O60602

Gene Accession:

BC109119

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.





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