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  • 产品名称:STRADB 抗原(重组蛋白)

  • 产品型号:100ug
  • 产品厂商:通蔚生物
  • 产品价格:800
  • 产品库存:35
  • 产品文档:
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详情介绍:

中文名称: STRADB 抗原(重组蛋白)

英文名称: STRADB Antigen (Recombinant Protein)

别     名:  STE20-related kinase adaptor beta; PAPK; ILPIP; ILPIPA; ALS2CR2; CALS-21; PRO1038

储     存:  冷冻(-20℃)

相关类别: 抗原

概     述:

Fusion protein corresponding to a region derived from 139-378 amino acids of human STRADB
    
技术规格

Full name:

STE20-related kinase adaptor beta

Synonyms:

PAPK; ILPIP; ILPIPA; ALS2CR2; CALS-21; PRO1038

Swissprot:

Q9C0K7

Gene Accession:

BC008302

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered, and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11, a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm, and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein, and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes, located on chromosomes 1 and 7, have been found for this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.





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