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  • 产品名称：AIM2抗原（重组蛋白）

  • 产品型号：1mg
  • 产品厂商：通蔚生物
  • 产品价格：3580
  • 产品库存：35
  • 产品文档：
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简单介绍：
AIM2抗原（重组蛋白）公司是一家专业从事生物科研项目的企业，经销优异化生物试剂，国内外知名品牌ELISA试剂盒，标准品|对照品，抗体，培养基，血清的科研生物产品，竭诚为您提供行内*全、*新的产品信息。欢迎来电咨询！
详情介绍：
中文名称： AIM2抗原（重组蛋白）

英文名称： AIM2 Antigen (Recombinant Protein)

别     名：  PYHIN4

储     存：  冷冻（-20℃）

相关类别： 抗原

概     述：

Fusion protein corresponding to a region derived from 138-337 amino acids of human AIM2

技术规格

Full name:

absent in melanoma 2

Synonyms:

PYHIN4

Swissprot:

O14862

Gene Accession:

BC010940

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Interferon-inducible protein AIM2 (Absent in melanoma 2) is a 343 amino acid protein belonging to the HIN-200 family. Induced by IFN-?, AIM2 is thought to act as a tumor suppressor by repressing NF?B transcriptional activity. Localized to the nucleus, AIM2 contains one DAPIN domain and one HIN-200 domain. The DAPIN domain is composed mostly of ?-helixes and is a protein-protein interaction domain capable of binding other DAPIN domains. The HIN-200 domain has been shown to bind directly to DNA, which, along with the binding of another protein ASC, results in the activation of Caspase-1.





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