别 名: X-ray repair cross complementing 4; SSMED
储 存: 冷冻(-20℃)
相关类别: 抗原
|
Full name: |
X-ray repair cross complementing 4 |
|
Synonyms: |
SSMED |
|
Swissprot: |
Q13426 |
|
Gene Accession: |
BC016314 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. This protein plays a role in both non-homologous end joining and the completion of V(D)J recombination. Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED). Alternative splicing generates several transcript variants. |
