英文名称: UBE4A Antigen (Recombinant Protein)
别 名: ubiquitination factor E4A; E4; UFD2; UBOX2
相关类别: 抗原
储 存: 冷冻(-20℃)
概 述
| Full name: | ubiquitination factor E4A | 
| Synonyms: | E4; UFD2; UBOX2 | 
| Swissprot: | Q14139 | 
| Gene Accession: | BC112367 | 
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE | 
| Expression system: | Escherichia coli | 
| Tags: | His tag C-Terminus, GST tag N-Terminus | 
| Background: | This gene encodes a member of the U-box ubiquitin ligase family. The encoded protein is involved in multiubiquitin chain assembly and plays a critical role in chromosome condensation and separation through the polyubiquitination of securin. Autoantibodies against the encoded protein may be markers for scleroderma and Crohn's disease. A pseudogene of this gene is located on the long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. | 

