英文名称: UBE2R2 Antigen (Recombinant Protein)
别 名: ubiquitin conjugating enzyme E2 R2; UBC3B; CDC34B; E2-CDC34B
相关类别: 抗原
储 存: 冷冻(-20℃)
概 述
| Full name: | ubiquitin conjugating enzyme E2 R2 | 
| Synonyms: | UBC3B; CDC34B; E2-CDC34B | 
| Swissprot: | Q712K3 | 
| Gene Accession: | BC004862 | 
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE | 
| Expression system: | Escherichia coli | 
| Tags: | His tag C-Terminus, GST tag N-Terminus | 
| Background: | Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation. | 

