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  • 产品名称:TUBGCP4 抗原(重组蛋白)

  • 产品型号:100ug
  • 产品厂商:通蔚生物
  • 产品价格:800
  • 产品库存:35
  • 产品文档:
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简单介绍:
TUBGCP4 抗原(重组蛋白)为了适应市场需要和长远发展,近年来,引进相关技术专业人才和消化国外先进的技术,不断进行产品和技术的更新改进,同时,完善的质量保证体系,提高企业的整体管理水平,一切努力和付出,惟愿助您一臂之力。
详情介绍:

中文名称: TUBGCP4 抗原(重组蛋白)

英文名称: TUBGCP4 Antigen (Recombinant Protein)

别     名:  tubulin gamma complex associated protein 4; 76P; GCP4; GCP-4; Grip76; MCCRP3
 
储     存:  冷冻(-20℃)

相关类别: 抗原

概     述

Fusion protein corresponding to a region derived from 468-667 amino acids of human TUBGCP4

技术规格

Full name:

tubulin gamma complex associated protein 4

Synonyms:

76P; GCP4; GCP-4; Grip76; MCCRP3

Swissprot:

Q9UGJ1

Gene Accession:

BC009870

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a component of the gamma-tubulin ring complex, which is required for microtubule nucleation. In mammalian cells, the protein localizes to centrosomes in association with gamma-tubulin. Crystal structure analysis revealed a structure composed of five helical bundles arranged around conserved hydrophobic cores. An exposed surface area located in the C-terminal domain is essential and sufficient for direct binding to gamma-tubulin. Mutations in this gene that alter microtubule organization are associated with microcephaly and chorioretinopathy. Alternative splicing results in multiple transcript variants.







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