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  • 产品名称：STAP1 抗原（重组蛋白）

  • 产品型号：1mg
  • 产品厂商：通蔚生物
  • 产品价格：3580
  • 产品库存：35
  • 产品文档：
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简单介绍：
STAP1 抗原（重组蛋白）以诚信为本，努力打造上等的品牌，为您提供全方位的售中、售后服务，具有上等的技术团队和上等的产品引入国内市场，满足国内广大客户的需求。
详情介绍：



中文名称： STAP1 抗原（重组蛋白）

英文名称： STAP1 Antigen (Recombinant Protein)

别     名：  signal transducing adaptor family member 1; BRDG1; STAP-1

相关类别： 抗原

储     存：  冷冻（-20℃）

概     述

Fusion protein corresponding to a region derived from 96-295 amino acids of human STAP1

技术规格

Full name:

signal transducing adaptor family member 1

Synonyms:

BRDG1; STAP-1

Swissprot:

Q9ULZ2

Gene Accession:

BC014958

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene contains a proline-rich region, a pleckstrin homology (PH) domain, and a region in the carboxy terminal half with similarity to the Src Homology 2 (SH2) domain. This protein is a substrate of tyrosine-protein kinase Tec, and its interaction with tyrosine-protein kinase Tec is phosphorylation-dependent. This protein is thought to participate in a positive feedback loop by upregulating the activity of tyrosine-protein kinase Tec. Variants of this gene have been associated with autosomal-dominant hypercholesterolemia (ADH), which is characterized by elevated low-density lipoprotein cholesterol levels and in increased risk of coronary vascular disease. Alternative splicing results in multiple transcript variants.







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