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  • 产品名称:SPRTN 抗原(重组蛋白)

  • 产品型号:1mg
  • 产品厂商:通蔚生物
  • 产品价格:3580
  • 产品库存:35
  • 产品文档:
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详情介绍:



中文名称: SPRTN 抗原(重组蛋白)

英文名称: SPRTN Antigen (Recombinant Protein)

别     名:  SprT-like N-terminal domain; DVC1; PRO4323; spartan; C1orf124

储     存:  冷冻(-20℃)

相关类别: 抗原

概     述

Fusion protein corresponding to a region derived from 1-243 amino acids of human SPRTN

技术规格

Full name:

SprT-like N-terminal domain

Synonyms:

DVC1; PRO4323; spartan; C1orf124

Swissprot:

Q9H040

Gene Accession:

BC015740

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene may play a role in DNA repair during replication of damaged DNA. This protein recruits valosin containing protein (p97) to stalled DNA replication forks where it may prevent excessive translesional DNA synthesis and limit the number of DNA-damage induced mutations. It may also be involved in replication-related G2/M-checkpoint regulation. Deficiency of a similar protein in mouse causes chromosomal instability and progeroid phenotypes. Mutations in this gene have been associated with Ruijs-Aalfs syndrome (RJALS). Alternatively spliced transcript variants have been identified.







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