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  • 产品名称：RFFL 抗原（重组蛋白）

  • 产品型号：100ug
  • 产品厂商：通蔚生物
  • 产品价格：800
  • 产品库存：35
  • 产品文档：
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简单介绍：
RFFL 抗原（重组蛋白）为感谢各大科研机构长期以来对我发货单的支持，我司特在精品发布的同时开展一周促销活动，主要形式为送礼活动，低至9折起售，凡买及送的哦！好机会不错过！了解详细信息来电咨询哦！也可以通过在本站留言的，我们一定在半个工作内给您回复。
详情介绍：
中文名称： RFFL 抗原（重组蛋白）

英文名称： RFFL Antigen (Recombinant Protein)

别     名：  ring finger and FYVE-like domain containing E3 ubiquitin protein ligase; CARP2; FRING; CARP-2; RNF189; RNF34L; RIFIFYLIN

储     存：  冷冻（-20℃）

相关类别： 抗原

概     述

Fusion protein corresponding to a region derived from 97-316 amino acids of human RFFL

技术规格

Full name:

ring finger and FYVE-like domain containing E3 ubiquitin protein ligase

Synonyms:

CARP2; FRING; CARP-2; RNF189; RNF34L; RIFIFYLIN

Swissprot:

Q8WZ73

Gene Accession:

BC028424

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

E3 ubiquitin-protein ligase that regulates several biological processes through the ubiquitin-mediated proteasomal degradation of various target proteins. Mediates 'Lys-48'-linked polyubiquitination of PRR5L and its subsequent proteasomal degradation thereby indirectly regulating cell migration through the mTORC2 complex. Also ubiquitinates the caspases CASP8 and CASP10, promoting their proteasomal degradation, to negatively regulate apoptosis downstream of death domain receptors. Also negatively regulates the tumor necrosis factor-mediated signaling pathway through targeting of RIPK1 to ubiquitin-mediated proteasomal degradation.





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