产品名称：兔抗TBP多克隆抗体

Background:

This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminus. This region of the protein modulates the DNA binding activity of the C terminus, and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription. The number of CAG repeats encoding the polyglutamine tract is usually 32-39, and expansion of the number of repeats increases the length of the polyglutamine string and is associated with spinocerebellar ataxia 17, a neurodegenerative disorder classified as a polyglutamine disease.

Applications:

ELISA, WB, IHC

Name of antibody:

TBP

Immunogen:

Full length fusion protein

Full name:

TATA box binding protein

Synonyms：

HDL4; GTF2D; SCA17; TFIID; GTF2D1

SwissProt:

P20226

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer and human gastric cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

38 kDa

WB Positive control:

231 cell，Human testis tissue，Hela and Hepg2 cell

WB Recommended dilution:

500-2000