产品名称：兔抗SPATA17多克隆抗体

Background:

Spata17 gene, which called MSRG11, by digital differential display of ESTs found only in testis. The deduced 292-amino acid protein was considered to be a member of the family of calmodulin (CaM)-binding proteins because it contained 3 short CaM-binding motifs containing conserved ile and gln residues (IQ motif). Spata17 protein was most abundant in the cytoplasm of round spermatids and elongating spermatids within seminiferous tubules of the ***** testis. Expression gradually decreased in the manipulated testis of animals that underwent experimental unilateral cryptorchidism. Transient transfection experiments with a Spata17 expression construct in cultured spermatogonia GC-1 cells indicated that Spata17 accelerated apoptosis in a dose-dependent manner.

Applications:

ELISA, WB, IHC

Name of antibody:

SPATA17

Immunogen:

Fusion protein of human SPATA17

Full name:

spermatogenesis associated 17

Synonyms：

IQCH, MSRG11, MSRG-11, RP11-144C20.1

SwissProt:

Q96L03

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human ovarian cancer and human cervical cancer

IHC Recommend dilution:

10-50

WB Predicted band size:

43 kDa

WB Positive control:

Human liver cancer tissue

WB Recommended dilution:

200-1000