英文名称： Anti-RNF126 rabbit polyclonal antibody
相关类别： 一抗
储 存： 冷冻（-20℃）
宿 主： Rabbit
抗 原： RNF126
反应种属： Human, Mouse, Rat
标 记 物： Unconjugate
克隆类型： rabbit polyclonal
技术规格
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Background: |
The protein encoded by this gene contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. RNF126 interacts with p21 and RNF126 over-expression increased p21 protein ubiquitination in an E3 ligase activity-dependent manner. RNF126 knockdown induced loss of cell viability in MDA-MB-231 and PC-3 can be partially rescued by depletion of p21. RNF126 stable knockdown in PC3 inhibited tumor growth in SCID mice. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
RNF126 |
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Immunogen: |
Synthetic peptide of human RNF126 |
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Full name: |
Ring finger protein 126 |
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SwissProt: |
Q9BV68 |
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ELISA Recommended dilution: |
1000-5000 |
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IHC positive control: |
Human thyroid cancer and Human brain |
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IHC Recommend dilution: |
25-100 |
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WB Predicted band size: |
38 kDa |
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WB Positive control: |
Jurkat and K562 cells |
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WB Recommended dilution: |
500-2000 |
