英文名称： Anti-RNF20 rabbit polyclonal antibody
别 名： BRE1; BRE1A; hBRE1
相关类别： 一抗
储 存： 冷冻（-20℃）
宿 主： Rabbit
抗 原： RNF20
反应种属： Human, Mouse
标 记 物： Unconjugate
克隆类型： rabbit polyclonal
技术规格
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Background: |
The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. The protein encoded by this human gene is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. This protein acts as a putative tumor suppressor and positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. In contrast, this protein also suppresses the expression of several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
RNF20 |
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Immunogen: |
Fusion protein of human RNF20 |
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Full name: |
ring finger protein 20, E3 ubiquitin protein ligase |
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Synonyms： |
BRE1; BRE1A; hBRE1 |
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SwissProt: |
Q5VTR2 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human esophagus cancer and human colon cancer |
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IHC Recommend dilution: |
10-50 |
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WB Predicted band size: |
114 kDa |
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WB Positive control: |
Hela, Jurkat, 231, A375, A172 and Lovo cells |
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WB Recommended dilution: |
500-2000 |
